There Is certainly interest in making use of conolidine as being a pain-reliever based upon evidence from animal research suggesting that it could reduce pain with no side effects of opioids (Flight, Nat Rev Drug Discov 2011). At first isolated with the bark of the tropical, ornamental flowering plant Tabernaemontana https://www.proleviate.com/post/conolidine-alkaloid-for-chronic-pain