Abstract Objectives Components of the hypothalamic-pituitary axis (HPA) pathway are potential mediators of the genetic risk of polycystic ovarian syndrome (PCOS). Impaired glucocorticoid receptor (NR3C1) expression and function may underlie impaired HPA-axis cortisol activity. thereby also contributing to the increased adrenal cortisol and androgen production present in women with PCO... https://www.lightemupsequences.com/