The protein kinase Mec1 (ATR ortholog) and its partner Ddc2 (ATRIP ortholog) play a key role in DNA damage checkpoint responses in budding yeast. Previous studies have established the model in which Ddc1. a subunit of the checkpoint clamp. and Dpb11. https://www.inmuebleslasmercedes.com/product-category/dessert-spoons/
Ddc2 mediates Mec1 activation through a Ddc1- or Dpb11-independent mechanism.
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